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Clin Chem Acta, 267: 197-211, 1997

224,225,226 Additionally, Klotho enhances insulin sensitivity in peripheral tissues, including muscle and adipose tissue, and has neuroprotective functions through the modulation of neuronal signaling pathways

5), have shown splendid delivery potential in both vitro and vivo studies, enhancing drug permeability across the ocular barriers and prolonging the residence time in the eye [23, 129]